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Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser
Published on: May 9, 2018
Long-term urinary sequelae following 125iodine prostate brachytherapy
Juanita Crook1, Neil Fleshner, Chris Roberts
1Department of Radiation Oncology, University Health Network, Princess Margaret Hospital, Toronto, Ontario, Canada.
The Journal of Urology
|November 13, 2007
Summary
Long-term urinary function after 125Iodine prostate brachytherapy is generally good, with most men experiencing no significant issues. A minority faced temporary urinary symptoms or required interventions, but persistent problems were rare.
Area of Science:
- Urology
- Oncology
- Radiation Oncology
Background:
- 125Iodine (125I) brachytherapy is a treatment for prostate cancer.
- Long-term urinary function data after this treatment are important for patient counseling.
Purpose of the Study:
- To evaluate long-term urinary function in men treated with 125I prostate brachytherapy without supplemental beam irradiation.
Main Methods:
- 484 men with favorable risk prostate cancer received 125I brachytherapy.
- Urinary function assessed pre-implant and post-implant using the International Prostate Symptom Score (IPSS).
- Urinary retention, catheterization, urgency, incontinence, stricture, and surgical intervention rates were recorded.
Main Results:
- 73.3% of men had no significant urinary sequelae beyond 1 year.
- 23% experienced a temporary IPSS flare; 3.4% required catheterization or surgery for retention.
- 0.8% had persistent urgency unresponsive to medication; 1% remained catheter-dependent long-term.
Conclusions:
- Late urinary morbidity occurred in 27% of men following 125I brachytherapy.
- Most patients responded well to medical or surgical management.
- Persistent urgency and catheter dependence were low (0.8% and 1%, respectively).
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