Related Experiment Video
Updated: Jul 10, 2026
07:36
Dissection of Imaginal Discs from 3rd Instar Drosophila Larvae
Published on: February 17, 2007
Richard Clothier: an appreciation.
1FRAME, Nottingham, UK. michael.balls@btopenworld.com
Alternatives to Laboratory Animals : ATLA
|November 16, 2007
Summary
Richard Clothier
Area of Science:
- Comparative immunology and toxicology.
- Development of in vitro cytotoxicity testing.
Background:
- Review of Richard Clothier's career and collaborations.
- Early work on Xenopus laevis lymphosarcoma aetiology and N-nitroso-N-methylurea effects on T-cells.
Discussion:
- Contributions to comparative immunology.
- Establishment of the FRAME Research Programme.
- Development and application of in vitro cytotoxicity tests for toxicity testing.
Key Insights:
- Led the FRAME Alternatives Laboratory at the University of Nottingham.
- Fostered collaborations with industrial partners and ECVAM.
- Significant contributions to the field of alternative testing methods.
Outlook:
- Continued advancement in alternative methods for toxicity assessment.
- Potential for further industrial and international collaborations.
- Legacy in promoting ethical and efficient scientific research.
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