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Updated: Jul 10, 2026

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
Published on: June 21, 2022
25 years of SA nodal cell modeling
1Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. r.wilders@amc.uva.nl
Abstract:
This review provides a brief history of modeling the spontaneous electrical activity of sinoatrial (SA) nodal cells. The first mathematical models of the pacemaker activity of these cells were published in the early 1980s. During the 25 years that followed, many more models of increasing complexity have been developed. The main characteristics of the twelve most widely used models are presented and compared.
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