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Updated: Jul 10, 2026

Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients
Published on: April 18, 2025
Non-invasive brain-computer interface system to operate assistive devices
Febo Cincotti1, Fabio Aloise, Simona Bufalari
1Laboratorio di Imaging Neuroelettrico e Brain Computer Interface, Fondazione Santa Lucia, IRCCS, Rome, 00179, Italy. f.cincotti@hsantalucia.it
Abstract:
In this pilot study, a system that allows disabled persons to improve or recover their mobility and communication within the surrounding environment was implemented and validated. The system is based on a software controller that offers to the user a communication interface that is matched with the individual's residual motor abilities. Fourteen patients with severe motor disabilities due to progressive neurodegenerative disorders were trained to use the system prototype under a rehabilitation program. All users utilized regular assistive control options (e.g., microswitches or head trackers) while four patients learned to operate the system by means of a non-invasive EEG-based Brain-Computer Interface, based on the subjects' voluntary modulations of EEG sensorimotor rhythms recorded on the scalp.

