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Updated: Jul 10, 2026
12:22
Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
Development of a multi-channel, portable optical topography system
Hirokazu Atsumori1, Masashi Kiguchi, Akiko Obata
1Advanced Research Laboratory, Hitachi, Ltd., 2520 Akanuma, Hatoyama, Saitama 350-0395, Japan. hirokazu.atsumori.et@hitachi.com
Summary
This study introduces a portable optical topography system for non-invasive brain monitoring. The new device allows for greater movement, successfully measuring brain activity during cognitive tasks.
Area of Science:
- Neuroscience
- Biomedical Engineering
- Medical Imaging
Background:
- Optical topography (OT) uses near-infrared spectroscopy (NIRS) for non-invasive brain oxygenation monitoring.
- Conventional OT systems are limited by optical fibers, restricting subject movement.
Purpose of the Study:
- To develop a novel, multi-channel, portable OT system without optical fibers.
- To assess the feasibility of the portable OT system for investigating brain function.
Main Methods:
- Development of a prototype multi-channel, portable OT system.
- Non-invasive measurement of oxygenated hemoglobin (oxy-Hb) and deoxygenated hemoglobin (deoxy-Hb) concentration changes.
- Utilizing the system to monitor frontal cortex activity during a word fluency task.
Main Results:
- The portable OT system successfully measured typical changes in oxy-Hb and deoxy-Hb concentrations.
- Hemoglobin concentration changes correlated with cognitive task performance.
- Demonstrated the system's capability for functional brain investigation.
Conclusions:
- The developed portable OT system offers enhanced mobility for brain function studies.
- This fiber-less system is a promising tool for non-invasive neuroscience research.
- The prototype enables investigation of frontal cortex activity during cognitive tasks.
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