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Updated: Jul 10, 2026

A Computational Modeling Approach to Investigate the Influence of Hyperthermia on the Tumor Microenvironment
Published on: December 1, 2023
Finite element analysis of the re-entrant type resonant cavity applicator for brain tumor hyperthermia
T Yabuhara1, K Kato, K Tsuchiya
1Department of Mechanical Engineering Informatics, Meiji University, Kawasaki, Japan. yabuhara@isc.meiji.ac.jp
Abstract:
In this paper, we have proposed a new heating method in which high frequency electric fields in a re-entrant type resonant cavity are used for the heating of deeply seated tumors. In this method, a human head is placed between the gap of the inner re-entrant cylinders, and is heated with electromagnetic fields stimulated in the cavity without contact between the surface of the human head and the applicator. Here, we proposed a new method to control the heating area. In this method, the resonant frequency inside the cavity was changed, then we use the TM010-like mode and the TM012-like mode from various types of the resonant frequency. First, the computer simulation results of electric and magnetic field patterns are presented. Second, a comparison of the heating properties of TM010-like mode and TM012-like mode are discussed. The heating area of the center of agar phantom is more concentrated by using TM012-like mode than that of using TM010-like mode. From these results, it is confirmed that the proposed method can be controlled to heat the various sizes of deep tumors.
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