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Related Experiment Videos

Left ventricular mass in normal Indian population.

S K Trivedi1, O P Gupta, A P Jain

  • 1Department of Medicine, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha.

Indian Heart Journal
|May 1, 1991
PubMed
Summary

This study determined normal left ventricular mass in Indian adults, finding it differs from Western populations. Upper limits were established for men and women, correlating with body size but not age.

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Area of Science:

  • Cardiology
  • Human Physiology
  • Medical Imaging

Background:

  • Left ventricular mass (LVM) assessment is crucial for cardiovascular health.
  • Establishing population-specific normal ranges is essential for accurate diagnosis.
  • Previous LVM data primarily reflects Western populations, potentially differing in Indian adults.

Purpose of the Study:

  • To ascertain the distribution of left ventricular mass in a normal adult Indian population.
  • To establish the upper limit of normal left ventricular mass for Indian men and women.
  • To investigate correlations between LVM and anthropometric/hemodynamic factors in this population.

Main Methods:

  • Prospective echocardiographic screening of 480 healthy Indian adults (310 men, 170 women).

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  • Estimation of left ventricular mass using standard echocardiographic formulas.
  • Statistical analysis to determine mean values, upper limits (mean + 2 SD), and correlations.

    • Main Results:

    • Mean LVM was 124 ± 32 gm in men and 93 ± 37 gm in women.
    • Upper limits of LVM were 189 gm for men and 167 gm for women.
    • LVM correlated significantly with body weight, height, and body surface area in both sexes.
    • LVM was independent of age but influenced by diastolic blood pressure in men.
    • Significant differences in LVM were observed compared to Western populations.

    Conclusions:

    • The study provides crucial reference ranges for LVM in the Indian population.
    • Established upper limits for LVM can aid in diagnosing cardiac conditions in Indian adults.
    • Observed differences highlight the need for population-specific cardiovascular reference values.