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Diffuse esophageal spasm.

Claudia Grübel1, Jan Borovicka, Werner Schwizer

  • 1Department of Gastroenterology and Hepatology, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.

The American Journal of Gastroenterology
|November 17, 2007
PubMed
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This review covers diffuse esophageal spasm (DES), detailing its clinical presentation, causes, and treatment options. It synthesizes current research on diagnosis and management strategies for DES patients.

Area of Science:

  • Gastroenterology
  • Esophageal Motility Disorders

Background:

  • Diffuse esophageal spasm (DES) is a primary esophageal motility disorder.
  • DES is characterized by uncoordinated and forceful esophageal contractions.

Purpose of the Study:

  • To provide a comprehensive review of diffuse esophageal spasm (DES).
  • To cover clinical features, pathophysiology, diagnosis, and management of DES.

Main Methods:

  • Literature search of the PubMed database for recent publications.
  • Keywords included "DES," "epidemiology," "prevalence," "diagnosis," "pathogenesis," and various treatment modalities.
  • Reference lists of identified papers were also reviewed.

Main Results:

  • The review synthesizes information on the epidemiology and prevalence of DES.

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  • It details the current understanding of DES pathophysiology.
  • Various diagnostic approaches and management strategies, including pharmacologic and surgical options, are discussed.

    • Conclusions:

    • Accurate diagnosis and tailored management are crucial for patients with DES.
    • Further research may refine understanding and treatment of this condition.