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Related Experiment Video

Updated: Jul 10, 2026

In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System
06:45

In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System

Published on: July 2, 2020

A patch antenna design for application in a phased-array head and neck hyperthermia applicator.

Margarethus M Paulides1, Jurriaan F Bakker, Nicolas Chavannes

  • 1Erasmus MC-Daniel den Hoed Cancer Center, Department of Radiation Oncology, Section Hyperthermia, PO Box 5201, NL-3008 AE, Rotterdam, The Netherlands. m.paulides@erasmusmc.nl

IEEE Transactions on Bio-Medical Engineering
|November 21, 2007
PubMed
Summary
This summary is machine-generated.

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This study optimized a patch antenna for head and neck cancer hyperthermia applicators. The designed antenna shows excellent performance, validating its suitability for clinical use in phased-array systems.

Area of Science:

  • Biomedical Engineering
  • Electromagnetics
  • Medical Physics

Background:

  • Hyperthermia therapy offers a promising approach for cancer treatment.
  • Effective delivery of hyperthermia requires specialized applicator antennas.
  • Patch antennas are suitable candidates for phased-array applicators due to their size and design flexibility.

Purpose of the Study:

  • To design and optimize a patch antenna for a clinical head and neck hyperthermia applicator.
  • To evaluate the antenna's performance using electromagnetic simulations and experimental validation.
  • To confirm the suitability of the patch antenna for phased-array clinical applications.

Main Methods:

  • Electromagnetic simulations were used to optimize the probe-fed patch antenna design at 433 MHz.

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  • Antenna dimensions were refined through iterative optimization steps.
  • Experimental validation was performed using a cylindrical setup with six antenna elements to measure impedance characteristics.

    • Main Results:

    • Optimized antenna design achieved a theoretical reflection of -38 dB and a bandwidth of 20 MHz (4.6%) at 433 MHz.
    • The antenna demonstrated stable electrical performance across a temperature range of 15-35°C and at patient-antenna distances as low as 4 cm.
    • Experimental measurements showed comparable results with -21 dB reflection and an 18.5 MHz bandwidth, validating simulation accuracy.

    Conclusions:

    • The designed patch antenna is highly suitable for clinical phased-array head and neck hyperthermia applicators.
    • The antenna design facilitates good central interference of fields from multiple elements.
    • Future work will involve verifying electrical performance in a prototype applicator.