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Related Experiment Video

Updated: Sep 17, 2025

Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics
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Development of a versatile deep hyperthermia treatment planning tool.

Tomas Drizdal1, Margarethus M Paulides2, Daniel de Jong3

  • 1Department of Radiotherapy, Erasmus MC, University Medical Center, Rotterdam, the Netherlands; Department of Biomedical Technology, Faculty of Biomedical Engineering, Czech Technical University in Prague, Kladno, Czech Republic.

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
|June 28, 2025
PubMed
Summary

A new deep hyperthermia treatment planning (HTP) tool with automatic patient positioning is faster and provides comparable target coverage to manual methods. This efficiency supports wider clinical adoption of HTP.

Keywords:
Deep hyperthermiaHyperthermia treatment planningPatient positioningSpecific absorption rate

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Area of Science:

  • Oncology
  • Medical Physics
  • Radiotherapy

Background:

  • Deep hyperthermia (HTP) is an effective cancer treatment modality.
  • Accurate treatment planning is crucial for optimal HTP efficacy.
  • Current manual planning can be time-consuming.

Purpose of the Study:

  • To develop and validate a versatile deep hyperthermia treatment planning (HTP) tool.
  • To implement and assess an automatic patient positioning routine within the HTP tool.
  • To compare the efficiency and accuracy of automatic versus manual HTP setup procedures.

Main Methods:

  • An automatic patient positioning routine was integrated into a new HTP tool.
  • Specific Absorption Rate (SAR) indicators (THQ, TC25, TC50) were compared between manual and automatic positioning for 118 patients (Sigma 60 and Sigma Eye applicators).
  • HTP setups were demonstrated for Sigma Ellipse, Alba4D, and AMC8 applicators.

Main Results:

  • The automatic positioning routine showed a maximum average relative difference of 2% for SAR indicators compared to manual positioning.
  • Automatic positioning significantly reduced operator time by 10-20 minutes per patient setup.
  • The tool demonstrated versatility across multiple applicator types.

Conclusions:

  • The automatic positioning routine in the HTP tool is time-efficient and achieves comparable SAR target coverage to manual methods.
  • Reduced planning time is expected to increase the clinical acceptance and implementation of HTP.
  • The developed HTP tool offers a versatile solution for deep hyperthermia treatment planning.