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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
[Primary signet ring cell bladder adenocarcinoma. Case report with a multidisciplinary therapeutical approach]
G H Cruz-Gonzáles1, R E Sánchez-Salas, K J Palmer-Román
1Universidad Central de Venezuela, Hospital Universitario de Caracas, Cátedra de Clínica Urológica, Servicio de Urología, Instituto Anatomopatológico Dr. "José Antonio O'Daly".
Introduction:
Bladder carcinoma is the second most frequent genitourinary tumor. Adenocarcinoma accounts for up to 0.5 to 2% of bladder carcinoma types. The pathology states the bladder adenocarcinomas are mucous secreting lesions with glandular, colloid or signet ring cell patterns. Even the important advances reached in the field of bladder carcinoma, yet less frequent lesions as bladder adenocarcinoma do not have a standarized treatment protocol.
Methods:
Case report of a patient with primary signet ring cell bladder adenocarcinoma with a therapeutical multidisciplinary approach. Literature review.
Results:
Patient's outcome and follow up, with regard of therapeutical implications based on pathological findings.
Conclusions:
Bladder adenocarcionoma is a rare oncological entity. Treatment protocols for these particular tumors are lacking. Multidisciplinary approach represents the best therapeutical intervention.
