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Published on: December 18, 2010
Experience with meconium peritonitis
So Hyun Nam1, Seong Chul Kim, Dae Yeon Kim
1Department of Pediatric Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul 138-736, South Korea.
Background:
Meconium peritonitis is a sterile chemical peritonitis resulting from intrauterine bowel perforation. With the development of neonatal care, the prognosis of meconium peritonitis improved much. We report our clinical experience.
Methods:
The medical records of patients with meconium peritonitis admitted to the Asan Medical Center from June 1989 to July 2006 were retrospectively reviewed.
Results:
Of 41 patients (17 males, 24 females), 38 (92.7%) were suspected to suffer from meconium peritonitis prenatally, at a median gestational age of 32 weeks (range, 21-40 weeks). The most common prenatal sonographic finding was fetal ascites followed by dilated bowel. Ten patients were managed conservatively, but 31 patients underwent operations including resection and anastomosis (22), drainage procedure (4), ileostomy (3) and primary repair (2). The operative 31 cases comprised generalized (16), fibroadhesive (10), and cystic types (5). The main causes were intestinal atresia and idiopathic bowel perforation. The mortality rate was 2.4%, and the morbidity rate was 34.1%.
Conclusions:
Good survival rate was achieved. But there was rather high morbidity. More gentle and delicate approach should be done to lower the morbidity.
Insights
Meconium peritonitis, a condition from intrauterine bowel perforation, has improved prognoses due to advanced neonatal care. This study reviews clinical experience, noting high survival but significant morbidity, suggesting a need for gentler treatment approaches.
Area of Science:
- Neonatal Surgery
- Pediatric Gastroenterology
- Fetal Medicine
Background:
- Meconium peritonitis is a sterile chemical peritonitis caused by intrauterine bowel perforation.
- Advances in neonatal care have significantly improved outcomes for meconium peritonitis.
- This study details clinical experiences with this condition.
Purpose of the Study:
- To review the clinical experience and outcomes of patients with meconium peritonitis.
- To analyze diagnostic findings, management strategies, and associated morbidities.
- To evaluate the effectiveness of current treatment approaches.
Main Methods:
- Retrospective review of medical records of patients with meconium peritonitis.
- Data collected from June 1989 to July 2006 at Asan Medical Center.
- Analysis of prenatal diagnosis, surgical interventions, and patient outcomes.
Main Results:
- Out of 41 patients, 92.7% were suspected prenatally, with fetal ascites and dilated bowel as common findings.
- Surgical intervention was required for 31 patients, with resection and anastomosis being the most common procedure.
- The study reported a low mortality rate (2.4%) but a high morbidity rate (34.1%).
Conclusions:
- A high survival rate was achieved in the management of meconium peritonitis.
- However, the morbidity rate remains a significant concern.
- A more delicate and conservative approach is recommended to reduce morbidity.
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