Lower motor neuron tetraparesis. Neuromuscular diseases

Generalized neuromuscular (lower motor neuron; LMN) diseases include those that affect neurons (neuronopathies), peripheral nerves (neuropathies), neuromuscular junctions (junctionopathies), and muscles (myopathies). These diseases cause diffuse clinical signs of LMN involvement. Although neuromuscular diseases occur relatively commonly in dogs, few syndromes have been well characterized in cats. Representative diseases within each of the major anatomic subcategories of neuromuscular disease are discussed.