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Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...

Pericarditis I: Introduction

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Location and Orientation of the Heart

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Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
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Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease

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Pericardial PEComa: echocardiographic features.

Reza Mollazadeh, Ali Reza Moaref, Mohammad Ghazinoor

International Journal of Cardiology

|November 21, 2007

Summary

This report details the first case of a pericardial PEComa, a rare tumor, found in a young man. The giant mass compressing the heart was successfully diagnosed and treated.

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Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease

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Published on: December 7, 2016

Area of Science:

Cardiovascular Pathology
Oncology
Thoracic Surgery

Background:

Perivascular Epitheloid Cell tumors (PEComas) are rare mesenchymal neoplasms with uncertain differentiation.
PEComas can occur in various locations, but pericardial involvement is exceptionally uncommon.
This case highlights a unique presentation of PEComa in the pericardial space.

Observation:

A 19-year-old male presented with dyspnea and chest pain.
Echocardiography revealed a large, posterior pericardial mass compressing the left atrium, with moderate pericardial effusion.
Histopathology confirmed neoplastic cells with HMB-45 positivity, characteristic of PEComa.

Findings:

The study describes the first documented case of a giant pericardial PEComa.
The tumor was successfully diagnosed through histopathological analysis and immunohistochemistry.
The patient experienced an uneventful six-month follow-up post-diagnosis.

Implications:

This case expands the known spectrum of PEComa locations.
It underscores the importance of considering rare tumors in the differential diagnosis of cardiac masses.
Further research into pericardial PEComas may improve diagnostic and therapeutic strategies.