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Comparative Performance, Procedural Characteristics and Safety of Micra Versus Aveir Leadless Pacemakers: Systematic
Hamidreza Soleimani1, Iman Razeghian2, Parham Dastjerdi3
1Department of Cardiology, School of Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Pacing and Clinical Electrophysiology : PACE
|April 15, 2026
Summary
Micra VR and Aveir VR leadless pacemakers show similar short-term safety and effectiveness. Minor differences in pacing thresholds and sensing exist, but further long-term studies are needed.
Area of Science:
- Cardiology
- Medical Devices
- Electrophysiology
Background:
- Leadless pacemakers (LPs) offer an alternative to transvenous systems, mitigating lead and pocket complications.
- Direct comparative data between single-chamber LPs like Micra VR and Aveir VR is limited.
Purpose of the Study:
- To systematically review and meta-analyze studies comparing the Micra VR and Aveir VR leadless pacemakers.
- To evaluate electrical performance, procedural metrics, and safety outcomes.
Main Methods:
- Systematic review and meta-analysis of four observational studies (757 patients).
- Searched PubMed, Embase, and Scopus databases through November 2025.
- Included studies reporting electrical performance, procedural metrics, or periprocedural complications.
Main Results:
- No significant differences in short-term pacing thresholds or impedance.
- Micra VR showed higher R-wave amplitudes in follow-up; Aveir VR had longer fluoroscopy times.
- Low and comparable rates of device dislodgement, effusion/tamponade, and overall complications between the two LPs.
Conclusions:
- Micra VR and Aveir VR demonstrate comparable short-term electrical performance, procedural efficacy, and safety.
- Observed minor differences likely reflect design and workflow variations.
- Further randomized controlled trials with extended follow-up are required to assess long-term outcomes.
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