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Updated: Jul 10, 2026

Quantification of the Respiratory Burst Response as an Indicator of Innate Immune Health in Zebrafish
Published on: September 12, 2013
Invertebrate immune systems specific, quasi-specific, or nonspecific?
1Centre for Sustainable Aquaculture Research, Department of Biological Sciences, Swansea University, Singleton Park, Swansea, UK. a.f.rowley@swansea.ac.uk
Abstract:
Until recently, it was widely accepted that invertebrates fail to show a high degree of specificity and memory in their immune strategies. Recent reports have challenged this view such that our understanding of the capabilities of the invertebrate immune systems needs to be reassessed. This account critically reviews the available evidence that suggests the existence of a high degree of memory and specificity in some invertebrates and seeks mechanistic explanations of such observations. It is postulated that elevated levels of phagocytosis may be a partial explanation for this phenomenon.
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