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Response of human pulps capped with different self-etch adhesive systems
M L R Accorinte1, A D Loguercio, A Reis
1Department of Dental Material, School of Dentistry, University of Brás Cubas, São Paulo, SP, Brazil.
Clinical Oral Investigations
|November 21, 2007
Summary
Calcium hydroxide cement is superior for pulp capping compared to two-step self-etch adhesives. Self-etch adhesives showed poor healing and inflammation, while calcium hydroxide promoted dentin bridge formation.
Area of Science:
- Dentistry
- Biomaterials Science
- Regenerative Medicine
Background:
- Pulp capping aims to preserve pulp vitality after exposure.
- Evaluating new materials for pulp capping is crucial for successful dental treatment.
Purpose of the Study:
- To compare the efficacy of calcium hydroxide cement versus two-step self-etch adhesive systems for direct pulp capping in humans.
- To assess the histological response of human pulps to these capping materials.
Main Methods:
- Human pulp exposures were treated with calcium hydroxide cement, Clearfil LB 2V, or Clearfil SE Bond.
- Teeth were restored and extracted after 30 and 90 days for histological analysis.
- Histological scoring assessed inflammatory response and dentin bridge formation.
Main Results:
- Self-etch adhesive systems (Clearfil LB 2V and SE) resulted in significantly worse pulpal responses at 90 days compared to controls.
- Moderate to severe inflammatory infiltrate and chronic abscesses were observed with self-etch adhesives.
- Calcium hydroxide groups demonstrated excellent healing with dentin bridge formation and minimal inflammation.
Conclusions:
- Calcium hydroxide cement is the recommended material for direct pulp capping due to superior healing outcomes.
- Two-step self-etch adhesive systems are contraindicated for direct human pulp capping.
- Further research may explore modifications to self-etch adhesives for improved biocompatibility.
