Related Experiment Video
Updated: Jul 10, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
Published on: April 3, 2014
Synthesis and properties of DNA duplexes containing cytosine analogs carrying phosphodiester functions
A T M Zafrul Azam1, Itaru Okamoto, Akira Ono
1Department of Material and Life Chemistry, Faculty of Engineering, Kanagawa University, 3-27-1 Rokkakubashi, Kanagawa-ku, Yokohama, Kanagawa 221-8686, Japan.
Abstract:
DNA duplexes containing cytosine residues bearing a phosphodiester function (X) were synthesized. The stability of the duplexes was investigated by UV-melting experiments.
More Related Videos
07:44Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
Published on: July 6, 2016
11:37Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
Published on: July 28, 2017
Related Concept Videos
Phosphodiester Linkages
Phosphodiester bond forms when a phosphoric acid molecule (H3PO4) links with two hydroxyl groups (–OH) of two other molecules, forming two ester bonds. Two water molecules are released in this process. The phosphodiester bond is commonly found in nucleic acids (DNA and RNA) and plays a critical role in their structure and function.
Phosphodiester Bonds Link Nucleotides Together
DNA and RNA are polynucleotides or long chains of nucleotides that are linked together. A nucleotide is...
DNA Base Pairing
Nucleic Acid Structure
DNA Structure
DNA has a double-helix structure. The...
Proofreading
Proofreading
Errors During Replication are Corrected by the DNA Polymerase Enzyme
The DNA Helix