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Synthesis of naphthyridine-conjugated DNA probes and their application to SNPs typing

Akio Kobori1, Takashi Mori, Asako Yamayoshi

  • 1Department of Biomolecular Engineering, Graduate School of Science and Technology, Kyoto Institute of Technology, Gosyokaidocho, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.

Nucleic Acids Symposium Series (2004)
|November 22, 2007
PubMed

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In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
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