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Screening for bladder cancer: a perspective.
Yair Lotan1, Robert S Svatek, Núria Malats
1Department of Urology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9110, USA. Yair.Lotan@UTSouthwestern.edu
Bladder cancer screening could improve survival by detecting the disease early. This review examines the benefits, risks, and cost-effectiveness of screening strategies for urinary bladder cancer.
Area of Science:
- Oncology
- Public Health
- Health Economics
Background:
- Bladder cancer is a prevalent malignancy globally, ranking as the seventh most common cancer in men and 17th in women.
- Urinary bladder cancer incurs substantial healthcare costs, being the fifth most expensive cancer in the US.
- Early detection through screening may significantly reduce patient morbidity and improve survival rates.
Purpose of the Study:
- To review the advantages and disadvantages of bladder cancer screening.
- To focus on the cost-effectiveness of implementing screening programs.
- To identify appropriate target populations for bladder cancer screening.
Main Methods:
- Literature review of existing studies on bladder cancer screening.
- Analysis of cost-effectiveness data for various screening strategies.
- Evaluation of risks and benefits associated with widespread screening.
Main Results:
- Screening can lead to earlier diagnosis of bladder cancer, potentially before muscle invasion or metastasis.
- The cost-effectiveness of screening is a critical factor in policy acceptance.
- Careful consideration of competing risks and benefits is necessary for successful screening implementation.
Conclusions:
- Bladder cancer screening holds promise for improving patient outcomes and survival.
- A thorough cost-effectiveness analysis is essential for determining the feasibility of screening programs.
- Defining specific populations for screening is crucial for optimizing resource allocation and maximizing benefits.
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