Plummer-Vinson syndrome successfully treated by endoscopic dilatation

Area of Science:

• Gastroenterology
• Hematology

Background:

• Plummer-Vinson syndrome (Paterson-Brown-Kelly syndrome) is a rare condition characterized by iron deficiency anemia, esophageal webs, and dysphagia.
• While iron repletion is crucial, esophageal webs often necessitate mechanical intervention.

Observation:

• A 69-year-old woman presented with a history of anemia and progressive dysphagia to solids.
• Diagnostic imaging revealed iron deficiency anemia and two cervical esophageal webs causing a severe stricture.

Findings:

• Intravenous iron supplementation improved anemia but not dysphagia.
• Endoscopic bougienage using sequentially larger dilators successfully disrupted the esophageal webs without complications.
• The patient experienced complete resolution of dysphagia post-procedure.

Implications:

• Endoscopic bougienage is a safe and effective treatment for severe esophageal stenosis associated with Plummer-Vinson syndrome.
• This minimally invasive approach offers a viable solution when iron therapy alone is insufficient.
• The procedure demonstrates rapid symptom relief and long-term efficacy.