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Updated: Jul 9, 2026

In Situ Lithiated Reference Electrode: Four Electrode Design for In-operando Impedance Spectroscopy
Published on: September 12, 2018
[Nephrogenic diabetes insipidus during lithium acute intoxication]
J Abodo1, V Seux, P Koffi-Dago
1Service de médecine interne et gériatrie, hôpital de Sainte-Marguerite, 270, boulevard de Sainte-Marguerite, 13274 Marseille cedex 09, France. abodo@ci.refer.org
Abstract:
Acute lithium intoxication may occur in circumstances causing kidney failure, when using lithium chronically. This situation may lead to neurological symptoms with coma, gastrointestinal disorders with diarrhea, cardiovascular symptoms with hypotension and metabolic symptoms with hypercalcemia. Nephrogenic diabetes insipidus may also develop. We report the case of a 69-year-old woman suffering from unipolar manic-depressive psychosis and treated by lithium for 10 years. This case highlights the need to monitor serum lithium levels in patients on long-term lithium regimens, especially in circumstances involving dehydration.
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