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Updated: Jul 9, 2026
05:22
Rapid Collection of Floral Fragrance Volatiles using a Headspace Volatile Collection Technique for GC-MS Thermal Desorption Sampling
Published on: December 10, 2019
Fragrance material review on trans-beta-damascone
A Lapczynski1, J Lalko, D McGinty
1Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA. alapczynski@rifm.org
Summary
This review examines the toxicologic and dermatologic effects of trans-beta-damascone, a common fragrance ingredient. Safety assessments indicate its suitability for cosmetic applications.
Area of Science:
- Toxicology
- Dermatology
- Cosmetic Science
Background:
- Trans-beta-damascone is widely utilized as a fragrance ingredient in various consumer products.
- Understanding its toxicologic and dermatologic profile is crucial for consumer safety.
Purpose of the Study:
- To conduct a comprehensive toxicologic and dermatologic review of trans-beta-damascone.
- To evaluate the safety of trans-beta-damascone for use in fragrance applications.
Main Methods:
- Literature review of existing toxicologic and dermatologic studies.
- Analysis of safety data related to skin sensitization, irritation, and systemic toxicity.
Main Results:
- Available data suggest a low potential for skin sensitization and irritation.
- No significant systemic toxicity concerns were identified at typical usage concentrations.
Conclusions:
- Trans-beta-damascone is considered safe for use as a fragrance ingredient based on current toxicologic and dermatologic evidence.
- Further research may be warranted to address specific exposure scenarios or novel applications.
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