Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Drug Toxicity: Allergic Reactions

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...

Sources of Food Contamination

Sources of Food Contamination

Contamination of food by microbial agents and natural toxins poses significant risks to public health. These hazards can be introduced at various points across the food supply chain, ranging from environmental sources to processing and storage stages. Understanding these contamination pathways is critical for developing strategies to ensure food safety.Seafood is particularly vulnerable to contamination through both environmental exposure and microbial colonization. Toxins from harmful algal...

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...

Staphylococcal Skin Infections

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

Accessory Structures of the Skin: Sebaceous Glands

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Are We Reading Patch Test Reactions in a Uniform Way? An International Contact Dermatitis Research Group Study.

Dermatitis : contact, atopic, occupational, drug·2025

Same author

Solute-Vehicle-Skin Interactions and Their Contribution to Pharmacokinetics of Skin Delivery.

Pharmaceutics·2025

Same author

Skin can Modulate the pH of Topical Creams and Gels.

AAPS PharmSciTech·2025

Same author

Headaches, Heart Block, and a Heart Tumor: Unusual Presentation of Malignant Melanoma.

Cureus·2025

Same author

Comment on Dinesen et al. Diphoterine for Chemical Burns of the Skin: A Systematic Review. <i>Eur. Burn J.</i> 2023, <i>4</i>, 55-68.

European burn journal·2024

Same author

Transdermal Drug Delivery Systems (TDDS): Recent Advances and Failure Modes.

Molecular pharmaceutics·2024

Search research articles

Related Experiment Video

Updated: Jul 9, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Contact dermatitis in agriculture.

Sahar Sohrabian¹, Howard Maibach

¹University of California-San Francisco, Dermatology Department, San Francisco, CA 94143-0989, USA.

Journal of Agromedicine

|November 23, 2007

Summary

Agricultural workers frequently experience dermatitis, but its causes and prevention are often overlooked. This study explores potential mechanisms and provides a diagnostic algorithm for this common skin condition.

Area of Science:

Agricultural medicine
Occupational dermatology

Background:

Dermatitis is a prevalent condition among agricultural workers.
The underlying mechanisms and preventive strategies for this occupational skin disease are not well-understood.

Purpose of the Study:

To investigate the potential mechanisms of dermatitis in agricultural workers.
To provide examples illustrating these mechanisms.
To propose an algorithm for the etiologic diagnosis of dermatitis in this population.

Main Methods:

Review of potential etiological factors and mechanisms of dermatitis in agricultural settings.
Development of a diagnostic algorithm based on clinical presentation and exposure history.

Main Results:

More Related Videos

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Published on: September 26, 2022

Related Experiment Videos

Last Updated: Jul 9, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Published on: September 26, 2022

Identification of various potential mechanisms contributing to agricultural dermatitis, including irritant contact dermatitis, allergic contact dermatitis, and phototoxic reactions.

Illustrative examples provided for each mechanism.

A structured algorithm for diagnosing the cause of dermatitis is presented.

Conclusions:

Dermatitis in agricultural workers requires further investigation into its mechanisms.
The proposed diagnostic algorithm can aid clinicians in identifying the etiologic factors of dermatitis in this occupational group.
Improved understanding and diagnosis can lead to better prevention strategies.