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Updated: Jul 9, 2026

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

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Steroids: partial synthesis in medicinal chemistry.

James R Hanson¹

¹Department of Chemistry, University of Sussex, Brighton, Sussex BN1 9QJ, UK.

Natural Product Reports

|November 23, 2007

Summary

This review covers steroid chemistry advancements from 2006, detailing reactions and synthesis of key compounds like estrogens, androgens, and vitamin D analogues. It highlights progress in steroid research and development.

Area of Science:

Organic Chemistry
Medicinal Chemistry
Biochemistry

Background:

Steroids are vital organic compounds with diverse biological functions.
Understanding steroid synthesis and reactions is crucial for drug discovery and development.
The year 2006 saw significant advancements in steroid chemistry research.

Purpose of the Study:

To comprehensively review the progress in steroid chemistry published in 2006.
To document key reactions and partial synthesis strategies for various steroid classes.
To provide a consolidated reference for researchers in the field.

Main Methods:

Literature review of scientific articles published between January and December 2006.
Categorization of research based on steroid classes (e.g., estrogens, androgens, pregnanes).

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Last Updated: Jul 9, 2026

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

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Published on: March 6, 2019

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Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library

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Analysis of reported chemical reactions and partial synthesis pathways.

Main Results:

Detailed coverage of reactions and partial synthesis for estrogens, androgens, pregnanes, bile acid derivatives, cholestanes, and vitamin D analogues.
Identification of emerging trends and novel methodologies in steroid synthesis.
Compilation of 159 relevant references for further study.

Conclusions:

The year 2006 was marked by substantial progress in steroid chemistry.
Continued research is essential for exploring new steroid derivatives and their applications.
This review serves as a valuable resource for the scientific community.