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Related Concept Videos

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...

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Related Experiment Video

Updated: Jul 9, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

Rheumatic chorea: relationship to systemic manifestations and response to corticosteroids.

Adrianne R Walker1, Lloyd Y Tani, Joel A Thompson

  • 1Department of Pediatrics, the University of Utah School of Medicine, Salt Lake City, Utah, USA.

The Journal of Pediatrics
|November 24, 2007
PubMed
Summary

Sydenham chorea affected one-third of children with rheumatic fever (RF). Prednisone shortened chorea duration, but some experienced recurrences and minor neurological issues.

Related Experiment Videos

Last Updated: Jul 9, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

Area of Science:

  • Pediatric Neurology
  • Rheumatology
  • Infectious Diseases

Background:

  • Rheumatic fever (RF) is an inflammatory condition following streptococcal infection.
  • Sydenham chorea (SC) is a prominent neurological manifestation of RF in children.
  • Understanding SC's characteristics and outcomes is crucial for pediatric care.

Purpose of the Study:

  • To characterize Sydenham chorea in a cohort of pediatric rheumatic fever patients.
  • To analyze demographic, clinical, and therapeutic aspects of SC.
  • To evaluate long-term sequelae and recurrence rates of SC.

Main Methods:

  • Retrospective analysis of a database of RF patients (1985-2002).
  • Identification of patients with SC and analysis of their characteristics.
  • Comparison of outcomes between treated and untreated SC patients.

Main Results:

  • SC occurred in 33% of 537 new-onset RF cases (median age 10 years).
  • SC patients were more often female and less likely to have carditis or arthritis.
  • Prednisone shortened chorea duration (4 vs. 9 weeks); 30% had recurrences, 20% reported residual symptoms.

Conclusions:

  • Sydenham chorea is a significant manifestation of RF in children.
  • SC patients may have a milder presentation of RF's rheumatologic complications.
  • Prednisone therapy can reduce chorea duration, though recurrences and sequelae are possible.