Related Experiment Video
Updated: Jan 21, 2026

Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar
Published on: May 30, 2025
[The characteristics of the development of experimental apical periodontitis in irradiation-induced immunodeficiency]
Abstract:
Apical periodontitis was induced in 24 mongrel dogs (16 experimental and 8 reference ones) over the course of total x-ray exposure. Analysis of clinical and physiologic data, hematologic parameters, and roentgenograms of the jaws of the two animal groups has shown the development of immunodeficiency state in the experimental animals due to exposure to ionizing irradiation in a dose of 1.5 Gy and an earlier development of destruction foci in bone tissue with diffuse involvement of the dental apexes.
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