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Mastitis unmasks Brugada syndrome.
Brugada syndrome, a cause of sudden cardiac death, can be triggered by fever. This case highlights a link between mastitis-induced fever and a temporary Brugada pattern in a postpartum woman.
Area of Science:
- Cardiology
- Genetics
- Internal Medicine
Background:
- Brugada syndrome is a primary cause of sudden cardiac death (SCD) in individuals without structural heart disease.
- Acute febrile illness is a known, yet under-recognized, precipitant for Brugada syndrome.
- No prior reports have documented an association between mastitis and Brugada syndrome.
Observation:
- An 18-year-old postpartum woman presented with mastitis, fever, and syncope.
- Electrocardiography demonstrated a type 1 Brugada pattern during the febrile episode.
- The Brugada pattern resolved upon fever abatement.
Findings:
- This case suggests mastitis-induced fever can unmask Brugada syndrome.
- The electrocardiographic findings indicate a transient Brugada pattern precipitated by fever.
- The role of pregnancy in Brugada syndrome remains unclear but warrants consideration.
Implications:
- Clinicians should consider Brugada syndrome in peripartum women presenting with fever and syncope.
- Fever associated with conditions like mastitis may precipitate Brugada syndrome in susceptible individuals.
- Awareness of fever as a trigger is crucial for managing sudden cardiac death risk in the peripartum period.
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