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Neuroendocrine dysregulations in sexually abused children and adolescents: a systematic review
I A E Bicanic1, M Meijer, G Sinnema
1University Medical Center Utrecht, Center for the Treatment of Psychotrauma in Children and Adolescents, 3508 AB, Utrecht, The Netherlands. i.a.e.bicanic@umcutrecht.nl
Abstract:
Several studies provided evidence for neuroendocrine dysregulations in adults with a history of child sexual abuse. This review focuses on neuroendocrine studies in sexually abused children and adolescents, dating from January 1, 1990 to January 1, 2007 and obtained from a systematic Medline Indexed literature search to identify endocrine correlates of child sexual abuse. Results from studies on hypothalamic-pituitary-adrenal axis (re)activity showed to be inconclusive. Studies on the sympathetic nervous system provided evidence for a higher baseline activity of this system in sexually abused children and adolescents. Factors contributing to divergent outcomes will be discussed and suggestions for future research will be presented.
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