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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Defenses Against Pathogens and Herbivores02:26

Defenses Against Pathogens and Herbivores

Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

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Updated: Jul 9, 2026

Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology
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Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology

Published on: August 23, 2024

Botanical ingredients in cosmeceuticals.

Leslie Baumann1

  • 1Division of Cosmetic Dermatology, University of Miami Cosmetic Center, Miami, FL 33140, USA.

Journal of Drugs in Dermatology : JDD
|November 28, 2007
PubMed
Summary

Complementary and alternative medicine (CAM), particularly herbal supplements, is increasingly popular for skin health. This review explores botanical compounds like curcumin and ginseng for their dermatologic benefits.

Area of Science:

  • Dermatology
  • Integrative Medicine
  • Pharmacognosy

Background:

  • Complementary and alternative medicine (CAM) use has significantly increased in the US over the last decade.
  • Herbal supplements, both oral and topical, are among the most common alternative therapies utilized.
  • Many herbal supplements feature botanical ingredients with extensive histories in traditional and folk medicine.

Purpose of the Study:

  • To review botanical compounds with potential or demonstrated dermatologic applications.
  • To highlight ingredients with long traditions, particularly in Asian medicine.
  • To discuss specific botanicals such as curcumin, Ginkgo biloba, ginseng, silymarin, soy, and tea tree oil.

Main Methods:

  • Literature review of botanical compounds used in traditional medicine.

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Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology
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Field Identification of Matricaria chamomilla using a Portable qPCR System
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Field Identification of Matricaria chamomilla using a Portable qPCR System

Published on: October 10, 2020

  • Focus on ingredients with documented or proposed dermatologic benefits.
  • Inclusion of both extensively studied and briefly considered agents.
  • Main Results:

    • Several botanical compounds, including curcumin, Ginkgo biloba, ginseng, silymarin, soy, and tea tree oil, show promise for dermatologic applications.
    • Many of these botanicals have a long history of use in Asian traditional medicine.
    • Some ingredients are already integrated into topical skincare formulations.

    Conclusions:

    • Botanical agents offer a range of potential dermatologic benefits.
    • Traditional medicine knowledge provides a basis for exploring novel skincare ingredients.
    • Further research may validate the efficacy and safety of these herbal supplements for various skin conditions.