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Updated: Jul 9, 2026
07:15
An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Probiotic and prebiotic influence beyond the intestinal tract
Irene Lenoir-Wijnkoop1, Mary Ellen Sanders, Michael D Cabana
1Danone Research, RD 128, Palaiseau, France.
Nutrition Reviews
|November 28, 2007
Summary
Probiotics and prebiotics benefit more than just gut health. These substances positively influence oral, stomach, and vaginal health, and may boost immunity for systemic benefits.
Area of Science:
- Microbiology
- Immunology
- Gastroenterology
Background:
- Probiotics and prebiotics are recognized for promoting gut health.
- Emerging research indicates their influence extends beyond the gastrointestinal tract.
Purpose of the Study:
- To explore the broader systemic effects of probiotics and prebiotics.
- To investigate mechanisms of action beyond the intestine.
Main Methods:
- Review of existing research on probiotics and prebiotics.
- Analysis of studies examining effects on oral, stomach, and vaginal microecology.
- Examination of immune-mediated systemic effects.
Main Results:
- Probiotics and prebiotics impact the microecology of the oral cavity, stomach, and vaginal tract.
- Systemic benefits include reduced severity of respiratory infections and allergy symptoms.
- Potential for decreased work or daycare absences due to improved health.
Conclusions:
- The influence of probiotics and prebiotics is more extensive than previously thought.
- Immune modulation is a likely mechanism for observed systemic effects.
- Further research is warranted to fully elucidate the broad-spectrum benefits.
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