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Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy
Published on: May 12, 2020
Ultraviolet transparent silicon oxynitride waveguides for biochemical microsystems.
Optics Letters
|November 28, 2007
Summary
Silicon oxynitride (SiO(x)N(y)) waveguides offer excellent UV performance for chemical analysis. These waveguides enable sensitive absorption measurements in biochemical microsystems, overcoming limitations of traditional materials.
Area of Science:
- Optical engineering
- Spectroscopy
- Materials science
Background:
- The ultraviolet (UV) wavelength region is crucial for chemical analysis via absorption spectroscopy.
- Germanium-doped silica waveguides, common in telecommunications, have limitations in UV light guidance below 400 nm due to UV-absorbing centers.
Purpose of the Study:
- To investigate the UV performance of silicon oxynitride (SiO(x)N(y)) waveguides.
- To demonstrate the applicability of these waveguides in biochemical microsystems for absorption measurements.
Main Methods:
- Fabrication and characterization of silicon oxynitride (SiO(x)N(y)) waveguides.
- Measurement of propagation loss in the UV-Vis spectrum (220-550 nm).
- Integration of waveguides with microfluidic channels for biochemical analysis.
Main Results:
- Silicon oxynitride (SiO(x)N(y)) waveguides demonstrated very good UV performance.
- Propagation loss was measured at approximately 1.0 dB/cm for 24-microm -wide waveguides in the 220-550 nm range.
- Successful absorption measurements of propranolol were performed at 212-215 nm, with a detection limit of 13 microM.
Conclusions:
- Silicon oxynitride (SiO(x)N(y)) waveguides are suitable for UV absorption spectroscopy.
- The integration with microfluidic channels enables sensitive biochemical analysis.
- These waveguides offer a viable alternative to germanium-doped silica for UV applications.

