Related Experiment Video
Updated: Jul 9, 2026

09:57
System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
Published on: April 5, 2017
[Direct nitrate reductase method of assessment of Mycobacterium tuberculosis susceptibility to drug]
Abstract:
Microbiological method of direct accelerated assessment of resistance of Mycobacterium tuberculosis to rifampicin and isoniazide was developed which is able to detect multidrug resistant M. tuberculosis 10-21 days after obtaining of sputum--4-5 times faster compared with the method of absolute concentrations. Efficacy of the method was 0.93 and 0.96 during assessment of susceptibility to rifampicin and isoniazide respectively.
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