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Cyclic vomiting syndrome: what a gastroenterologist needs to know
Namita Pareek1, David R Fleisher, Thomas Abell
1University of Mississippi Medical Center, Jackson, Mississippi, USA.
Cyclic vomiting syndrome (CVS) is more common than previously believed, particularly in adults, and is linked to migraines. Early diagnosis and systematic treatment are crucial for managing this disabling condition.
Area of Science:
- Gastroenterology
- Neurology
- Genetics
Background:
- Cyclic vomiting syndrome (CVS) is a functional disorder affecting all age groups.
- Previously considered rare with unknown causes, treatment relied on anecdotal evidence.
- Recent research indicates CVS is more prevalent than initially thought.
Purpose of the Study:
- To review the current understanding of cyclic vomiting syndrome.
- To highlight the association between CVS and migraine headaches.
- To emphasize the importance of prompt diagnosis and effective treatment strategies.
Main Methods:
- A comprehensive literature review was conducted.
- Searches were performed using internet and Medline databases.
- Data was compiled as of April 2006.
Main Results:
- CVS is more common than previously recognized, especially in adults.
- CVS shares features with migraine headaches and has a genetic link to mitochondrial DNA.
- Prompt diagnosis is essential to prevent morbidity, requiring exclusion of mimicking disorders.
Conclusions:
- CVS is recognized as a distinct disorder within the migraine spectrum.
- Effective treatment is achievable once patients receive a proper diagnosis.
- Increased research and recognition since the 1990s are improving outcomes for patients with CVS.
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