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Updated: Jul 9, 2026

Using the Overlay Assay to Qualitatively Measure Bacterial Production of and Sensitivity to Pneumococcal Bacteriocins
Published on: September 30, 2014
Spermicidal bacteriocins: lacticin 3147 and subtilosin A
Lara Silkin1, Shereen Hamza, Susan Kaufman
1Department of Chemistry, University of Alberta, Edmonton, Alta., Canada T6G 2G2.
Abstract:
Spermicidal compounds that also exhibit antimicrobial properties would be extremely attractive agents as they could be used to not only prevent unwanted pregnancy but also to combat the growing prevalence of sexually transmitted infections (STI). One class of compounds that are potential candidates for development of dual-acting contraceptive products are antimicrobial peptides (AMPs). Herein, we report preliminary studies carried out to investigate the spermicidal activity of two bacteriocins, lacticin 3147 and subtilosin A, on bovine, horse/pony, boar and rat sperm.
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