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Hypopyon iritis after primary fresh amniotic membrane transplantation.
Renuka Srinivasan1, Suchi Smitha T, Arvind Gupta
1Department of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Cornea
|November 29, 2007
Summary
Sterile hypopyon iritis occurred after a primary amniotic membrane transplant (AMT) using fresh amniotic membrane (AM). Treatment with periocular steroids resolved the condition, highlighting a potential complication and its management.
Area of Science:
- Ophthalmology
- Regenerative Medicine
Background:
- Pseudophakic bullous keratopathy can cause significant visual impairment.
- Amniotic membrane transplantation (AMT) is a therapeutic option for ocular surface diseases.
- Fresh amniotic membrane (AM) is utilized in ocular reconstructive surgery.
Observation:
- A case report details a 65-year-old male patient receiving a primary AMT with fresh AM for bullous keratopathy.
- The patient developed hypopyon iritis on the second postoperative day.
- Initial treatment with periocular antibiotics was ineffective, but periocular steroids led to resolution.
Findings:
- Post-AMT sterile hypopyon iritis is a potential complication.
- Cultures of the amniotic membrane and contact lens were negative, indicating a sterile inflammatory process.
- Recurrence of hypopyon was noted due to poor patient compliance, responding again to steroids.
Implications:
- This case highlights the importance of recognizing sterile hypopyon iritis as a complication of fresh AMT.
- Periocular steroids appear effective in managing this post-transplant inflammatory response.
- Patient compliance is crucial for successful outcomes following AMT.
