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[Dialysis treatment of infants with end stage failure]
Heidi Vihovde Sandvig1, Alice Gustavsen, Rønnaug Solberg
1Det medisinske fakultet, Universitet i Oslo.
Insights
Long-term dialysis is now a viable treatment for infants with end-stage renal failure, serving as a crucial bridge to kidney transplantation. This approach, involving peritoneal dialysis or haemodialysis, offers a lifesaving alternative for infants with chronic kidney disease.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
Background:
- End-stage renal failure in infants is a rare condition.
- Previously considered untreatable, advancements now enable life-saving interventions.
- Renal replacement therapy and dialysis techniques have improved significantly.
Purpose of the Study:
- To present and evaluate long-term dialysis in infants with end-stage renal failure.
- To compare outcomes with other dialysis centers.
- To establish dialysis as a feasible bridge to transplantation.
Main Methods:
- Case study of three infants with end-stage renal failure shortly after birth.
- Treatment involved long-term dialysis as a bridge to kidney transplantation.
- Comparison of results with data from other dialysis centers.
Main Results:
- All three infants were successfully dialyzed until transplantation.
- Two patients received peritoneal dialysis, and one received haemodialysis.
- Complications were infrequent and manageable, aligning with previous research.
Conclusions:
- Long-term dialysis for infants with chronic renal failure is a proven alternative to experimental treatment.
- Dialysis serves as a critical bridge until transplantation is feasible.
- Treatment success is influenced by co-morbidity and requires a multidisciplinary team and parental cooperation.
Background:
End stage renal failure in infants is rare, and was until recently regarded as untreatable. Advancements in dialysis techniques and other renal replacement therapy, have now made lifesaving treatment possible.
Material And Methods:
Three infants who developed end stage renal failure shortly after birth and were subsequently treated with long-term dialysis (as a bridge to transplantation) are presented and their results are compared with those from other dialysis centres.
Results And Interpretation:
All three patients were successfully dialysed until transplantation, two with peritoneal dialysis and one with haemodialysis. Complications were rare and manageable. The results are in accordance with findings from previous studies. Long-term dialysis in infants with chronic renal failure should no longer be considered experimental and is now a real alternative until the child is big enough to have a transplantation. Treatment outcome is affected by co-morbidity. The treatment requires a multidisciplinary approach with specialists from many fields including paediatrics, paediatric surgery, nephrology, nutrition and dialysis. In addition it is essential to cooperate with the parents, as the treatment is demanding for the family as well as for the medical personnel.
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