Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transcriptional regulation.

Peter G Okkema1, Michael Krause

  • 1Laboratory of Molecular Biology, University of Illinois at Chicago, Chicago, IL 60607, USA. okkema@uic.edu

Wormbook : the Online Review of C. Elegans Biology
|December 1, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Artificial Muscles: Electrostatic Actuation and Design Tradeoffs.

Biomimetics (Basel, Switzerland)·2026
Same author

Atomic Layer Deposition Processes: Versatile Platforms for Engineering ZnO-Chitosan Biointerfaces.

Advanced healthcare materials·2026
Same author

Application and performance of the novel Elcomat 5000 autocollimator in slope-measuring profilometry of beamline optics.

The Review of scientific instruments·2026
Same author

Fetal Pillow Deflates: Low-Lithotomy Caesarean Delivers.

BJOG : an international journal of obstetrics and gynaecology·2025
Same author

Low-lithotomy cesarean section for the impacted fetal head.

American journal of obstetrics and gynecology·2024
Same author

Experimental Proof of Principle of 3D-Printed Microfluidic Benthic Microbial Fuel Cells (MBMFCs) with Inbuilt Biocompatible Carbon-Fiber Electrodes.

Micromachines·2024
Same journal

Caenorhabditis nomenclature.

WormBook : the online review of C. elegans biology·2018
Same journal

Tubulins in C. elegans.

WormBook : the online review of C. elegans biology·2018
Same journal

History of research on C. elegans and other free-living nematodes as model organisms.

WormBook : the online review of C. elegans biology·2017
Same journal

Development, structure, and maintenance of C. elegans body wall muscle.

WormBook : the online review of C. elegans biology·2016
Same journal

Working with dauer larvae.

WormBook : the online review of C. elegans biology·2016
Same journal

Small GTPases.

WormBook : the online review of C. elegans biology·2016
See all related articles

This chapter reviews gene transcription regulation in C. elegans, detailing transcription factor binding and promoter function. It examines methods and limitations, highlighting specific promoter elements and spatial gene expression mechanisms.

Area of Science:

  • Molecular Biology
  • Developmental Biology
  • Genetics

Background:

  • Transcription regulation in Caenorhabditis elegans shares similarities with other eukaryotes.
  • Understanding specific transcription factor binding and their roles as activators or repressors is ongoing.
  • Characterization of transcription factors and their binding sites is increasing.

Purpose of the Study:

  • To review general concepts of promoter function in C. elegans.
  • To discuss methods employed and limitations encountered in studying C. elegans transcription.
  • To provide examples of complex promoter regulation and spatial gene expression.

Main Methods:

  • Review of existing literature on C. elegans transcription.
  • Analysis of specific cis-acting promoter elements (myo-2, hlh-1, lin-26).

Related Experiment Videos

  • Discussion of organ-, tissue-, and cell type-specific gene expression mechanisms.

    • Main Results:

    • General concepts of promoter function in C. elegans have emerged.
    • Specific promoter elements and their regulatory roles are being identified.
    • Mechanisms for spatial gene expression specificity are being elucidated.

    Conclusions:

    • C. elegans transcription regulation offers insights applicable to other organisms.
    • Further research is needed to fully understand transcription factor-promoter interactions.
    • Complex promoters and spatial gene expression are regulated by multiple sequence elements.