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[CT evolution of nasal steroid management of chronic rhinosinusitis]

Luo Zhang1, Cheng-shuo Wang, De-min Han

  • 1Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Beijing Tongren Hospital of Capital University of Medical Sciences, Beijing Institute of Otorhinolaryngology, Beijing 100730, China. luozhang@trhos.com

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery
|December 7, 2007
PubMed

Insights

Topical steroid treatment effectively reduced symptoms and improved imaging in nonpolypoid chronic sinusitis patients. Most patients showed significant improvement, reducing the need for surgery.

Area of Science:

  • Otolaryngology
  • Pharmacology

Background:

  • Nonpolypoid chronic sinusitis presents a therapeutic challenge.
  • Topical steroid efficacy in this specific subtype requires further investigation.

Purpose of the Study:

  • To evaluate the effectiveness of topical steroid treatment for nonpolypoid chronic sinusitis in both adult and pediatric populations.

Main Methods:

  • Two cohorts (11 pediatric, 13 adult) with nonpolypoid chronic sinusitis were treated with nasal budesonide.
  • Treatment duration averaged 7-7.5 weeks with daily dosages of 128-256 microg/d.
  • Lund scores and patient-reported symptoms were assessed pre- and post-treatment.

Main Results:

  • Significant reductions in Lund scores were observed in both adult (P < 0.01) and pediatric (P < 0.01) groups.
  • CT imaging showed a cure rate of 38% in adults and 73% in children.
  • Adult patient self-assessment correlated with initial symptom severity (r = 0.676, P < 0.05).

Conclusions:

  • Topical steroid therapy is highly effective for nonpolypoid chronic sinusitis.
  • The majority of patients experienced significant symptom relief and improved sinus conditions.
  • Surgical intervention was infrequently required following this treatment regimen.
Abstract

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