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Pleural Effusion II: Symptoms and Management

Pleural Effusion II: Symptoms and Management

Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:

Pleural Effusion I: Introduction

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Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
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Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Pneumothorax-II

Pneumothorax-II

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Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Pleura of the Lungs

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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...

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Updated: Jul 9, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

[A case of tuberculous pleurisy with a rapid decrease in pleural effusion].

Hirokazu Tokuyasu¹, Etsuko Watanabe, Ryota Okazaki

¹Divisions of Respiratory Medicine, Matsue Red Cross Hospital.

Nihon Kokyuki Gakkai Zasshi = the Journal of the Japanese Respiratory Society

|December 7, 2007

Summary

This summary is machine-generated.

This case study highlights a rare instance of tuberculous pleurisy where levofloxacin rapidly reduced pleural effusion. Standard antituberculous therapy led to complete resolution in a patient with a history of aortitis syndrome.

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Area of Science:

Pulmonology
Infectious Diseases
Medical Case Reports

Background:

Presents a rare case of tuberculous pleurisy in a 73-year-old woman with a history of aortitis syndrome treated with corticosteroids.
The patient presented with dyspnea on exertion, indicative of respiratory compromise.

Observation:

Chest roentgenogram revealed left pleural effusion characterized as exudative with lymphocyte predominance.
Elevated adenosine deaminase levels were noted in the pleural fluid.
Initial treatment with levofloxacin for one week resulted in a remarkable decrease in pleural effusion.

Findings:

Mycobacterium tuberculosis was identified in cultures from bronchial lavage fluid and sputum.
Levofloxacin demonstrated a rapid, albeit temporary, reduction in pleural effusion.
Subsequent standard antituberculous therapy (isoniazid, rifampicin, ethambutol) achieved complete resolution of the condition.

Implications:

This case underscores the potential role of fluoroquinolones like levofloxacin in the initial management of tuberculous pleurisy, particularly for rapid symptom relief.
Highlights the importance of prompt diagnosis and appropriate antituberculous therapy for favorable outcomes.
Suggests that early intervention with antibiotics may help manage symptoms while awaiting definitive microbiological confirmation and treatment initiation.