Related Experiment Video
Updated: Jul 9, 2026

07:57
A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
[Masked depression--history and present days].
Anna Miodek1, Paweł Szemraj, Józef Kocur
1Provincial Specialistic Hospital, Poland. ania@miodek.net
Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|December 7, 2007
Summary
Masked depression, a form of atypical depression, presents with somatic complaints rather than typical mood symptoms. Despite not being in current diagnostic manuals, it affects millions and requires proper identification to prevent severe consequences.
Area of Science:
- Psychiatry
- Clinical Psychology
Context:
- Masked depression, historically termed 'atypical depression' or 'hidden depression', was recognized in the mid-to-late 20th century.
- Characterized by somatic symptoms without clear organic causes, its depressive features were often subtle or absent.
Purpose:
- To highlight the continued relevance of masked depression despite its exclusion from current diagnostic systems like ICD-10 and DSM-IV.
- To underscore the diagnostic challenges and significant negative outcomes associated with this condition.
Summary:
- Masked depression manifests as physical ailments, obscuring underlying psychological distress.
- Though not explicitly classified in ICD-10 or DSM-IV, it is estimated to comprise 6-7% of all depressive disorders.
- Historical terms include depression equivalent, vegetative equivalent, and depression without depression.
Impact:
- Lack of diagnosis leads to severe somatic and psychological consequences for patients.
- Improper treatment negatively impacts social and professional life, potentially increasing suicide rates.
- Delayed or incorrect diagnosis results in substantial healthcare costs and patient suffering.
Related Concept Videos
Depressive Disorders: MDD and Dysthymia
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Depression: Overview
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Depressive Disorders: Etiology
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Long-term Depression
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Long-term Depression
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Calcium Ion Concentration Mechanism
If over time, all...
Diagnostic and Statistical Manual of Mental Disorders (DSM)
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...

