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Gold nanoparticles with perfluorothiolate ligands.

Amala Dass1, Rui Guo, Joseph B Tracy

  • 1Kenan Laboratories of Chemistry, University of North Carolina, Chapel Hill, NC 27599-3290, USA.

Langmuir : the ACS Journal of Surfaces and Colloids
|December 7, 2007
PubMed
Summary

Two new syntheses produced smaller gold nanoparticles (Au NPs) using fluorinated ligands. These fluorous gold nanoparticles exhibit unique solubility properties compared to their non-fluorinated counterparts.

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Area of Science:

  • Nanotechnology
  • Materials Science
  • Organic Chemistry

Background:

  • Gold nanoparticles (Au NPs) are widely studied for their unique optical and electronic properties.
  • Functionalization of Au NPs with specific ligands is crucial for tuning their characteristics and applications.
  • Fluorinated compounds offer distinct properties, including hydrophobicity and chemical stability, making them attractive for surface modification.

Purpose of the Study:

  • To develop novel synthetic routes for gold nanoparticles functionalized with fluorinated ligands.
  • To characterize the size, composition, and properties of the resulting fluorous gold nanoparticles.
  • To compare the properties of these fluorous Au NPs with existing gold nanoparticle systems.

Main Methods:

  • Synthesis of fluorous Au NPs using fluorinated alkyl and aryl thiolate ligands.

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  • Characterization techniques including MALDI-mass spectrometry, thermogravimetric analysis (TGA), 19F NMR, HPLC, TEM, and optical spectroscopy.
  • Electrochemical analysis to discern specific core sizes within polydisperse mixtures.

    • Main Results:

    • Two distinct synthetic methods yielded fluorous Au NPs in the 44-75 Au atom size range, smaller than previous fluor-capped examples.
    • Fluoroalkyl thiolate-protected Au NPs were a mixture of approximately 44 and 75 core atoms.
    • Ligand replacement reactions produced polydisperse mixtures, with a discernible Au75 core species.
    • The synthesized fluorous nanoparticles exhibited solubility characteristic of perfluorinated materials.

    Conclusions:

    • Successful synthesis of novel fluorous gold nanoparticles using two different approaches.
    • The fluorous Au NPs possess distinct physicochemical properties, including unique solubility profiles.
    • These findings open avenues for new applications of functionalized gold nanoparticles in areas requiring fluorinated materials.