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Relationship between subjective and objective cognitive function in the early and late prodrome
Frauke Schultze-Lutter1, Stephan Ruhrmann, Heinz Picker
1University of Cologne, Department of Psychiatry and Psychotherapy, Early Recognition and Intervention Centre for Mental Crises (FETZ), 50924 Cologne, Germany. frauke.schultze-lutter@uk-koeln.de
Cognitive deficits in psychosis prodrome are often unrelated between subjective feelings and objective tests. However, early prodromal states may show subtle links, aiding prediction.
Area of Science:
- Psychiatry
- Neuroscience
- Cognitive Psychology
Background:
- Cognitive disturbances are observed in individuals with psychosis prodromal symptoms.
- The relationship between subjective and objective cognitive deficits across different prodromal states remains unclear.
Purpose of the Study:
- To investigate the interplay between subjective and objective cognitive measures in various psychosis prodromal states.
Main Methods:
- Assessed subjective and objective cognitive deficits in participants with early (n=33) or late (n=69) prodromal states.
- Utilized the Schizophrenia Proneness Instrument and a comprehensive neuropsychological test battery.
Main Results:
- Individuals in the early prodromal state exhibited less impairment compared to those in the late state.
- Subjective and objective cognitive deficits were generally unrelated.
- An exception was observed between time-limited neurocognitive speed and subjectively reduced stress tolerance, particularly in the early prodromal group.
Conclusions:
- Subjective and objective cognitive deficits in psychosis prodrome typically provide complementary, predictive information.
- Potential associations between subjective and objective cognitive measures may be more discernible in the early, less impaired prodromal stage.
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