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Related Experiment Video

Updated: Jul 9, 2026

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Published on: February 14, 2021

Receding horizon controller for the baroreceptor loop in a model for the cardiovascular system.

Mark Mutsaers¹, Mostafa Bachar, Jerry Batzel

¹Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.

Cardiovascular Engineering (Dordrecht, Netherlands)

|December 7, 2007

Summary

This study introduces receding horizon control (RHC) as an alternative to linear quadratic control (LQR) for the human cardiovascular system (CVS) baroreceptor loop. RHC offers a new method for stabilizing the CVS model under workload.

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Area of Science:

Physiology
Control Systems Engineering
Biomedical Engineering

Background:

The human cardiovascular system (CVS) relies on the baroreceptor reflex for blood pressure regulation.
Previous models utilized linear quadratic control (LQR) to stabilize the CVS under ergometric workload.
Receding horizon control (RHC) presents a potential alternative for baroreflex control.

Purpose of the Study:

To design and implement RHC for the baroreceptor loop of a human CVS model.
To evaluate RHC as an alternative to the established LQR strategy.
To compare the performance of RHC against LQR using experimental data.

Main Methods:

A receding horizon control (RHC) strategy was designed and implemented.
The RHC was applied to a previously developed model of the human cardiovascular system (CVS).
Control parameters for the RHC cost functional were estimated using existing experimental data.

Main Results:

The RHC implementation was successfully designed and applied to the CVS model.
Performance metrics of the RHC were compared directly against the LQR implementation.
The study provides a comparative analysis of RHC versus LQR for baroreflex control.

Conclusions:

Receding horizon control (RHC) is a viable alternative for modeling the baroreceptor loop in the human cardiovascular system (CVS).
The RHC approach offers a different control strategy for stabilizing the CVS.
Further research can explore RHC's efficacy in various physiological conditions.