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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
Published on: September 21, 2017
Synthesis of anthraquinone oligonucleotides for triplex stabilization
Zhengyun Zhao1, Guomei Peng, Jan Michels
1School of Chemistry, University of Southampton, Highfield, Southampton, United Kingdom.
Nucleosides, Nucleotides & Nucleic Acids
|December 7, 2007
Abstract:
The synthesis of two anthraquinone phosphoramidites is described. In both cases the anthraquinone moiety is attached via a linker to the 5-position of a uracil base, allowing incorporation at any thymidine position in an oligonucleotide sequence. Anthraquinone-modified oligonucleotides have potential applications as triplex stabilizers and fluorescence quenchers.
