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Updated: Jul 9, 2026

Probiotic Studies in Neonatal Mice Using Gavage

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

Probiotics in children.

Benjamin Kligler¹, Patrick Hanaway, Andreas Cohrssen

¹Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10463, USA. bkligler@chpnet.org

Pediatric Clinics of North America

|December 7, 2007

Summary

This summary is machine-generated.

Probiotics are safe for children and can help prevent antibiotic-associated diarrhea and reduce infectious diarrhea duration. Specific strains are less critical than adequate dosage (5-10 billion CFUs daily) and product quality.

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Area of Science:

Pediatrics
Microbiology
Immunology

Background:

Gastrointestinal flora is crucial for children's immune and digestive health.
Probiotics are recognized for their safety in pediatric populations.
Existing research highlights probiotics' role in managing specific gastrointestinal issues.

Purpose of the Study:

To review the role of probiotics in pediatric health.
To assess the efficacy of probiotics in preventing and treating various childhood conditions.
To provide guidance on probiotic use in children, focusing on dosage and quality.

Main Methods:

Literature review of studies on probiotics in pediatric health.
Analysis of clinical evidence for probiotic efficacy in diarrhea, necrotizing enterocolitis, and atopic dermatitis.
Evaluation of recommendations regarding probiotic strains, dosage, and product quality.

Main Results:

Probiotics are safe for healthy children.
Probiotics effectively reduce antibiotic-associated diarrhea and acute infectious diarrhea duration.
Potential benefits include preventing community-acquired diarrhea, reducing necrotizing enterocolitis risk in premature infants, and aiding atopic dermatitis management.

Conclusions:

Probiotics offer significant benefits for pediatric gastrointestinal and immunologic health.
Adequate dosage (5-10 billion CFUs/day or higher) is key, with strain specificity less critical.
Clinicians must be aware of product variability and ensure quality for optimal outcomes.