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Phase preparation in steady-state free precession MR elastography.

Jens Rump1, Carsten Warmuth, Jürgen Braun

  • 1Department of Radiology, Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, 10117 Berlin, Germany.

Magnetic Resonance Imaging
|December 8, 2007
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Summary

This study introduces a new method for magnetic resonance elastography (MRE) using balanced steady-state free precession (bSSFP) imaging. The technique improves motion sensitivity without requiring extensive shimming, reducing scan times for better in vivo imaging.

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Area of Science:

  • Medical Imaging
  • Biophysics
  • Magnetic Resonance Imaging

Background:

  • Balanced steady-state free precession (bSSFP) imaging demands high magnetic field homogeneity for accurate strain and motion measurements.
  • Nonlinear signal responses to spin phase variations in bSSFP complicate motion quantification.

Purpose of the Study:

  • To develop a novel technique for enhancing motion sensitivity in bSSFP imaging for magnetic resonance elastography (MRE).
  • To reduce the need for pre-scan shimming, thereby decreasing overall examination time.

Main Methods:

  • Utilized background gradients to introduce strong in-plane spin phase variations in bSSFP sequences.
  • Applied spatial filtering, common in MRE, to remove low phase-to-noise ratio bands.
  • Demonstrated the technique in vivo on human liver and heart tissues.

Main Results:

  • Generated periodic patterns of increased motion sensitivity within bSSFP images.
  • Achieved wave images equivalent to uniform phase response after spatial filtering.
  • Successfully applied the phase preparation technique to selectively amplify wave signal amplitude in MRE.

Conclusions:

  • The proposed phase preparation technique enhances motion sensitivity in bSSFP-MRE without prior shimming.
  • This method simplifies MRE acquisition, reduces scan time, and improves wave signal amplitude.
  • In vivo human liver and heart imaging demonstrated the clinical applicability of phase-prepared bSSFP-MRE.