[Histopathology of 73 cases of calcifying epithelioma]

In this paper, 73 patients with calcifying epithelioma are reported. It comprised 0.094% of all our total biopsies and occurred in children as well as in adults of all ages despite the fact that most of the patients were children and youngsters (70.2%). Fourty-seven were female and 26 male. The lesion developed slowly into small masses with prolonged clinical course. The majority (88.5%) of the lesions were 0.5-1.5 cm in size usually located in the head, face, neck and the upper extremities. This tumor was composed of two cell types: the shadow cells and basophilic cells. The shadow cells were found in 100% of the cases from the beginning to the end whereas the basophilic cells reduced gradually with time. Ossification was observed in 21% of the cases, and increasing with time. In 86% of cases, calcification was observed.