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Updated: Jul 9, 2026

Spatiotemporal Mapping of Motility in Ex Vivo Preparations of the Intestines
Published on: January 27, 2016
Effects of intestinal electrical stimulation on postprandial small-bowel motility and transit in dogs
1University of Texas Medical Branch, Division of Gastroenterology, Route 0632, Room 221 Microbiology Bldg., 1108 The Strand, Galveston, TX 77555-0632, USA.
Background:
Intestinal electrical stimulation (IES) with long pulses has been reported to inhibit motility as well as accelerate transit of continuous infusion. However, it is unknown whether there is a correlation between the IES-induced alterations in motility and transit and whether there is a difference in transit during IES between continuous infusion and bolus infusion.
Methods:
The study was performed in 2 postprandial sessions (control and stimulation) in dogs with 2 pairs of serosal electrodes and 2 intestinal cannulas. Intestinal motility and transit with and without IES were measured by manometry and phenol red, respectively.
Results:
IES significantly decreased intestinal motility and increased transit time. There was a significant correlation between motility index and transit during IES.
Conclusions:
IES inhibits both intestinal bolus motility and transit. There is correlation between motility and transit during IES.
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