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[Fertility and pregnancy after conization].

A Kalitsaris1, M Paschopoulos, E Paraskevaidis

  • 1Ospedale Accademico San Bonifatius (EMS), Lingen, Germania Federale.

Annali Di Ostetricia, Ginecologia, Medicina Perinatale
|July 1, 1991
PubMed
Summary

Conization for cervical cancer prevention in women of fertile age has a 13.51% pregnancy rate post-operation. The study suggests conization does not significantly increase premature birth risk, potentially negating the need for preventive cerclage.

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Area of Science:

  • Gynecology
  • Oncology
  • Reproductive Medicine

Background:

  • Conization is a common procedure for cervical cancer prevention in women of reproductive age.
  • Assessing the impact of conization on subsequent pregnancies and birth outcomes is crucial for patient counseling.

Purpose of the Study:

  • To evaluate the rate of postoperative pregnancies after conization.
  • To assess the incidence of premature births before and after conization.
  • To determine the necessity of preventive cerclage following conization.

Main Methods:

  • Retrospective analysis of 408 women under 40 who underwent conization between 1967 and 1989.
  • Data collection on postoperative pregnancy rates and birth outcomes, including premature births.
  • Comparison of premature birth rates with and without preventive cerclage.

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Main Results:

  • A 13.51% postoperative pregnancy rate was observed, decreasing with age.
  • The rate of premature births decreased from 15.25% pre-operation to 13.31% post-operation.
  • Preventive cerclage was used in 8.1% of cases, with 5.4% having no cerclage, showing similar outcomes.

Conclusions:

  • Conization does not appear to significantly increase the risk of premature birth.
  • Preventive cerclage may not be routinely necessary after conization due to the low risk of premature birth.
  • Conization is a viable option for cervical cancer prevention with manageable obstetric outcomes.